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Substance Use Prevention and Harm Reduction

Opioid Misuse and Overdose Prevention

Opioids, both prescription painkillers and illegal drugs such as heroin and illicitly manufactured fentanyl, are responsible for most of the 52,000 deaths of Americans every year from overdose. States and localities have implemented a number of legal and regulatory interventions to address this epidemic.

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Opioid Misuse and Overdose

Opioids

The United States remains in the grip of an unprecedented epidemic of drug-related harm. In 2017, over 70,000 Americans were killed by drug overdose, surpassing the number lost at the height of the HIV/AIDS crisis. Opioids, both prescription painkillers and illegal drugs such as heroin and illicitly manufactured fentanyl, are responsible for most of these deaths.

States and localities have implemented a number of legal and regulatory interventions to address this epidemic. These include the creation and strengthening of prescription monitoring programs (PMPs), drug take-back programs and initiatives to increase access to naloxone, a medication that effectively reverses opioid overdose. States are also taking measures to increase access to evidence-based substance use disorder treatment, improve prescriber training, and evaluate whether existing programs are having the desired effect.

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